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Journal article

Personalised Estimation of the Arterial Input Function for Improved Pharmacokinetic Modelling of Colorectal Cancer Using dceMRI

Abstract:

dceMRI is becoming a key modality for tumour characterisation and monitoring of response to therapy, because of the ability to identify the underlying tumour physiology. Pharmacokinetic (PK) models relate the contrast enhancement seen in dceMRI to physiological parameters but require accurate measurement of the AIF, the time-dependant contrast concentration in blood plasma. In this study, a novel method is introduced that overcomes the challenges of direct AIF measurement, by automatically es...

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Publication status:
Published

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Authors


Bhushan, M More by this author
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Journal:
ABDOMINAL IMAGING: COMPUTATION AND CLINICAL APPLICATIONS
Volume:
8198
Pages:
126-135
Publication date:
2013
DOI:
EISSN:
1611-3349
ISSN:
0302-9743
URN:
uuid:eacbaf1a-a8b9-4bb0-9553-a1be04d94ba6
Source identifiers:
439428
Local pid:
pubs:439428

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