Addition of sodium criterion to SOAR stroke score

Adekunle-Olarinde, I; McCall, S; Barlas, R; Wood, A; Clark, A; Bettencourt-Silva, J; Metcalf, A; Bowles, K; Soiza, R; Potter, J; Myint, P

Journal article

Addition of sodium criterion to SOAR stroke score

Abstract:: Objectives

To examine the usefulness of including sodium (Na) levels as a criterion to the SOAR stroke score in predicting inpatient and 7-day mortality in stroke.

Materials and Methods

Data from the Norfolk and Norwich University Hospital Stroke and TIA register (2003-2015) were analysed. Univariate and then multivariate models controlling for SOAR variables were used to assess the association between admission sodium levels and inpatient and 7-day mortality. The prognostic ability of the SOAR and SOAR-Na score for mortality outcomes at both time points were then compared using Area Under the Curve (AUC) values from Receiver Operating Characteristics.

Results

A total of 8,493 cases were included (male=47.4%, mean (s. d.) 77.7 (11.6) years). Compared to normonatraemia (135-145mmol/L), hypernatraemia (>145mmol/L) was associated with inpatient mortality and moderate (125-129mmol/L) and severe hypontraemia (<125mmol/L) with 7-day mortality after adjustment for stroke type, Oxfordshire Community Stroke Project classification, age, pre-stroke modified Rankin score and sex. The SOAR and SOAR-Na scores both performed well in predicting inpatient mortality with AUC values of 0.794(0.78-0.81) and 0.796(0.78-0.81), respectively. 7-day mortality showed similar results. Both scores were less predictive in those with chronic kidney disease (CKD) and more so in those with hypoglycaemia.
Conclusion

The SOAR-Na did not perform considerably better than the SOAR stroke score. However, the performance of SOAR-Na in those with CKD and dysglycaemias requires further investigation.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Adekunle-Olarinde, I., McCall, S., Barlas, R., Wood, A., Clark, A., Bettencourt-Silva, J., Metcalf, A., Bowles, K., Soiza, R., Potter, J., & Myint, P. (2016). Addition of sodium criterion to SOAR stroke score. Acta Neurologica Scandinavica, 135(5), 553–559.

MLA Style

Adekunle-Olarinde, I, et al. “Addition of Sodium Criterion to SOAR Stroke Score.” Acta Neurologica Scandinavica, vol. 135, no. 5, 2016, pp. 553–59.

Chicago Style

Adekunle-Olarinde, I, S McCall, R Barlas, et al. 2016. “Addition of Sodium Criterion to SOAR Stroke Score.” Acta Neurologica Scandinavica 135 (5): 553–59.
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