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A bioinformatics search pipeline, RNA2DSearch, identifies RNA localization elements in Drosophila retrotransposons.

Abstract:

mRNA localization is a widespread mode of delivering proteins to their site of function. The embryonic axes in Drosophila are determined in the oocyte, through Dynein-dependent transport of gurken/TGF-alpha mRNA, containing a small localization signal that assigns its destination. A signal with a similar secondary structure, but lacking significant sequence similarity, is present in the I factor retrotransposon mRNA, also transported by Dynein. It is currently unclear whether other mRNAs exis...

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Publication status:
Published

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Publisher copy:
10.1261/rna.1264109

Authors


Hamilton, RS More by this author
Hartswood, E More by this author
Van De Bor, V More by this author
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Journal:
RNA (New York, N.Y.)
Volume:
15
Issue:
2
Pages:
200-207
Publication date:
2009-02-05
DOI:
EISSN:
1469-9001
ISSN:
1355-8382
URN:
uuid:eac37c41-52f5-4eda-92e8-517ac86480d7
Source identifiers:
99984
Local pid:
pubs:99984

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