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Radiosynthesis and evaluation of [18F]Selectfluor bis(triflate).

Abstract:
(Figure Presented) Selectfluor, one of the most reactive and commonly used electrophilic fluorinating N-F reagents, has been radiolabeled with 18F. The resulting new [18F]-labeled N-F reagent is safe, nontoxic, and easy to handle. The combined use of [18F]Selectfluor bis(triflate) and AgOTf allows for the preparation of electron-rich 18F-aromatic compounds through a simple "shake and mix" protocol at room temperature (see scheme; SA=specific activtiy). © 2010 Wiley-VCH Verlag GmbH and. Co. KGaA, Weinheim.
Publication status:
Published

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Publisher copy:
10.1002/anie.201002310

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Institution:
University of Oxford
Department:
Oxford, MSD, Population Health
Role:
Author
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Journal:
Angewandte Chemie (International ed. in English)
Volume:
49
Issue:
38
Pages:
6821-6824
Publication date:
2010-09-05
DOI:
EISSN:
1521-3773
ISSN:
1433-7851
URN:
uuid:eabcab7a-ae39-478c-9ddf-5108104cda73
Source identifiers:
67466
Local pid:
pubs:67466

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