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Angiogenin is up-regulated in the nucleus and cytoplasm in human primary breast carcinoma and is associated with markers of hypoxia but not survival.

Abstract:

Angiogenin, a 14.2 kD polypeptide that was originally noted for its angiogenic activity, is now increasingly recognized to have a multiplicity of biological roles in both physiological and pathological conditions. In breast cancer, there are conflicting studies questioning the role of angiogenin. Here, the pattern of expression of angiogenin during the transition from normal breast tissue to ductal carcinoma in situ and invasive carcinoma is reported together with the correlates between the l...

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Publication status:
Published

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Publisher copy:
10.1002/path.1740

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences
Gatter, KC More by this author
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Journal:
The Journal of pathology
Volume:
205
Issue:
5
Pages:
585-591
Publication date:
2005-04-05
DOI:
EISSN:
1096-9896
ISSN:
0022-3417
URN:
uuid:eab0b165-fcbb-4864-945d-026cb321b5bf
Source identifiers:
119188
Local pid:
pubs:119188

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