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Journal article

Corpus callosum involvement is a consistent feature of amyotrophic lateral sclerosis.

Abstract:

OBJECTIVE: While the hallmark of amyotrophic lateral sclerosis (ALS) is corticospinal tract in combination with lower motor neuron degeneration, the clinical involvement of both compartments is characteristically variable and the site of onset debated. We sought to establish whether there is a consistent signature of cerebral white matter abnormalities in heterogeneous ALS cases. METHODS: In this observational study, diffusion tensor imaging was applied in a whole-brain analysis of 24 heterog...

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Publication status:
Published

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Authors


Filippini, N More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
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Journal:
Neurology
Volume:
75
Issue:
18
Pages:
1645-1652
Publication date:
2010-11-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:ea920672-30a6-473c-bfb6-98c99754cb44
Source identifiers:
139517
Local pid:
pubs:139517

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