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Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure.

Abstract:

A region with a major effect on blood pressure (BP) is located on rat chromosome 1 in the vicinity of the Sa gene, a candidate gene for BP regulation. Previously, we observed a single linkage peak for BP in this region in second filial generation rats derived from a cross of the spontaneously hypertensive rat (SHR) with the Wistar-Kyoto rat (WKY), and we have reported the isolation of the region containing the BP effect in reciprocal congenic strains (WKY.SHR-Sa) and (SHR.WKY-Sa) derived from...

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Publication status:
Published

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Publisher copy:
10.1161/01.hyp.38.2.216

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Hypertension More from this journal
Volume:
38
Issue:
2
Pages:
216-221
Publication date:
2001-08-01
DOI:
EISSN:
1524-4563
ISSN:
0194-911X
Language:
English
Keywords:
Pubs id:
pubs:29709
UUID:
uuid:ea7f9c02-8ced-4737-9fc6-ce4391369751
Local pid:
pubs:29709
Source identifiers:
29709
Deposit date:
2012-12-19

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