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Antibodies to human papillomavirus and to other genital infectious agents and invasive cervical cancer risk.

Abstract:

Human papillomaviruses (HPVs) play an important part in the development of cervical cancer, but the role of other infectious agents, such as herpes simplex virus (HSV), is not clear. We assayed serum samples collected from 219 women with cervical cancer and from 387 controls for antibody to infectious agents. HPV 16-E7 and/or HPV 18-E7 antibodies were significantly related to cervical cancer risk (RR 1.9, 95% CI 1.2-3.2). Antibodies to HSV types 1 and 2, Chlamydia trachomatis, and to multiple...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Cancer Epidemiology Unit
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Journal:
Lancet
Volume:
341
Issue:
8853
Pages:
1116-1118
Publication date:
1993-05-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:ea7c5db0-41e8-4104-9363-4bb824ff660c
Source identifiers:
35788
Local pid:
pubs:35788

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