Effect of distal embolization on myocardial perfusion reserve after percutaneous coronary intervention: a quantitative magnetic resonance perfusion study.

Journal article

BACKGROUND: Studies have shown that a subset of patients demonstrate persistent impairment in microcirculatory function after percutaneous coronary intervention (PCI). Distal embolization of plaque contents has been postulated as the main mechanism for this. We sought to investigate this further by evaluating PCI-induced changes in myocardial perfusion reserve index (MPRI) over time in segments with "distal-type" procedure-related myonecrosis using high-resolution quantitative cardiovascular...

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Authors: Selvanayagam, J; Cheng, A; Jerosch-Herold, M; Rahimi, K; Porto, I

• Publication status: Published
• Journal: Circulation
• Volume: 116
• Issue: 13
• Pages: 1458-1464
• Publication date: 2007-09-01
• DOI: 10.1161/circulationaha.106.671909
• EISSN: 1524-4539
• ISSN: 0009-7322
• Language: English
• Keywords: Myocardium; Middle Aged; Stents; Aged; Cohort Studies; Humans; Coronary Circulation; Coronary Stenosis; Microcirculation; Coronary Restenosis; Male; Female; Single-Blind Method; Necrosis; Angioplasty, Balloon, Coronary; Magnetic Resonance Imaging; Sampling Studies; Perfusion; Magnetic Resonance Imaging, Cine; Embolism