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Human immunodeficiency virus-specific T lymphocyte cell

Abstract:

Recent developments in HIV-specific CTL quantification (staining with MHC-epitopic peptide tetramers and IFNγ production) have shed new light on human immunodeficiency virus (HIV)-specific cytotoxic T lymphocytes (CTL). One week after infection, anti-HIV CTLs quickly appear, with a weak specificity spectrum which broaden afterwards. During the asymptomatic stage, an equilibrum between host and virus exists, characterized by vigourous CTL responses (frequencies: 10-2 to 10-3 CD8 T cells) direc...

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
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Journal:
Virologie
Volume:
5
Issue:
1
Pages:
23-34
Publication date:
2001-01-01
ISSN:
1267-8694
URN:
uuid:ea61bbfe-4bc5-4608-875b-13ae6442d18b
Source identifiers:
94342
Local pid:
pubs:94342
Language:
French
Keywords:

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