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Journal article

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk.

Abstract:

BACKGROUND: Carotid intima-media thickness (cIMT) is a widely accepted marker of subclinical atherosclerosis. To date, large-scale investigations of genetic determinants of cIMT are sparse. METHODS AND RESULTS: To identify cIMT-associated genes and genetic variants, a discovery analysis using the Illumina 200K CardioMetabochip was conducted in 3430 subjects with detailed ultrasonographic determinations of cIMT from the IMPROVE (Carotid Intima Media Thickness [IMT] and IMT-Progression as Predi...

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Publication status:
Published

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Authors


Sennblad, B More by this author
Strawbridge, RJ More by this author
Zabaneh, D More by this author
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Journal:
Circulation. Cardiovascular genetics
Volume:
5
Issue:
6
Pages:
656-665
Publication date:
2012-12-05
DOI:
EISSN:
1942-3268
ISSN:
1942-325X
URN:
uuid:ea4c1aba-3dfb-4923-91f4-7731e794d425
Source identifiers:
363828
Local pid:
pubs:363828

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