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A concise approach to the synthesis of all twelve 5-deoxyhexoses: D-tagatose-3-epimerase-a reagent that is both specific and general

Abstract:

2-Deoxy-d-glucitol and 2-deoxy-d-allitol, both prepared as crystalline polyols from d-erythronolactone, are oxidized by Gluconobacter thailandicus NBRC 3254 to 5-deoxy-d-threo-hexulose [5-deoxy-d-fructose = 5-deoxy-l-sorbose] and 5-deoxy-d-erythro-hexulose [5-deoxy-l-psicose = 5-deoxy-d-tagatose], respectively. d-Tagatose-3-epimerase (DTE) equilibrates 5-deoxy-d-fructose to 5-deoxy-d-psicose and 5-deoxy-l-psicose to 5-deoxy-l-fructose, providing substrates for the preparation of all eight d- ...

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Publication status:
Published

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Publisher copy:
10.1016/j.tetlet.2009.03.061

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Journal:
TETRAHEDRON LETTERS More from this journal
Volume:
50
Issue:
26
Pages:
3559-3563
Publication date:
2009-07-01
DOI:
ISSN:
0040-4039
Language:
English
Pubs id:
pubs:41241
UUID:
uuid:ea44fb52-ba64-4154-a524-002f9be1f87b
Local pid:
pubs:41241
Source identifiers:
41241
Deposit date:
2012-12-19

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