Journal article

Mixed vector immunization with recombinant adenovirus and MVA can improve vaccine efficacy while decreasing antivector immunity

Abstract:: Substantial protection can be provided against the pre-erythrocytic stages of malaria by vaccination first with an adenoviral and then with an modified vaccinia virus Ankara (MVA) poxviral vector encoding the same ME.TRAP transgene. We investigated whether the two vaccine components adenovirus (Ad) and MVA could be coinjected as a mixture to enhance protection against malaria. A single-shot mixture at specific ratios of Ad and MVA (AdMVA) enhanced CD8 ++ T cell-dependant protection of mice ag...
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APA Style

Reyes-Sandoval, A., Rollier, C., Milicic, A., Bauza, K., Cottingham, M. G., Tang, C., Dicks, M. D., Wang, D., Longley, R., Wyllie, D., & Hill, A. (2012). Mixed vector immunization with recombinant adenovirus and MVA can improve vaccine efficacy while decreasing antivector immunity. Molecular Therapy, 20(8), 1633–1647.

MLA Style

Reyes-Sandoval, A., et al. “Mixed Vector Immunization with Recombinant Adenovirus and MVA Can Improve Vaccine Efficacy While Decreasing Antivector Immunity.” Molecular Therapy, vol. 20, no. 8, 2012, pp. 1633–47.

Chicago Style

Reyes-Sandoval, A, C Rollier, A Milicic, K Bauza, MG Cottingham, C Tang, MD Dicks, et al. 2012. “Mixed Vector Immunization with Recombinant Adenovirus and MVA Can Improve Vaccine Efficacy While Decreasing Antivector Immunity.” Molecular Therapy 20 (8): 1633–47.
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Publisher copy:: 10.1038/mt.2012.25

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+ Reyes-Sandoval, A More by this author

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+ Rollier, C More by this author

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+ Milicic, A More by this author

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+ Bauza, K More by this author

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+ Cottingham, MG More by this author

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Bibliographic Details

Journal:: Molecular Therapy More from this journal
Volume:: 20
Issue:: 8
Pages:: 1633-1647
Publication date:: 2012-08-01
DOI:: 10.1038/mt.2012.25
EISSN:: 1525-0024
ISSN:: 1525-0016

Item Description

Language:: English
Pubs id:: pubs:348832
UUID:: uuid:ea36f5db-4269-4456-a950-31c3baeb7343
Local pid:: pubs:348832
Source identifiers:: 348832
Deposit date:: 2012-12-19

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Copyright date:: 2012

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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