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Journal article

Social inequality and the syndemic of chronic disease and COVID-19: county-level analysis in the USA

Abstract:

Background: Given the effect of chronic diseases on risk of severe COVID-19 infection, the present pandemic may have a particularly profound impact on socially disadvantaged counties.

Methods: Counties in the USA were categorised into five groups by level of social vulnerability, using the Social Vulnerability Index (a widely used measure of social disadvantage) developed by the US Centers for Disease Control and Prevention. The incidence and mortality from COVID-19, and the prevalence of major chronic conditions were calculated relative to the least vulnerable quintile using Poisson regression models.

Results: Among 3141 counties, there were 5 010 496 cases and 161 058 deaths from COVID-19 by 10 August 2020. Relative to the least vulnerable quintile, counties in the most vulnerable quintile had twice the rates of COVID-19 cases and deaths (rate ratios 2.11 (95% CI 1.97 to 2.26) and 2.42 (95% CI 2.22 to 2.64), respectively). Similarly, the prevalence of major chronic conditions was 24%–41% higher in the most vulnerable counties. Geographical clustering of counties with high COVID-19 mortality, high chronic disease prevalence and high social vulnerability was found, especially in southern USA.

Conclusion: Some counties are experiencing a confluence of epidemics from COVID-19 and chronic diseases in the context of social disadvantage. Such counties are likely to require enhanced public health and social support.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/jech-2020-215626

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Sub department:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0003-3982-4325
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Author
ORCID:
0000-0003-0139-2934


Publisher:
BMJ Publishing Group
Journal:
Journal of Epidemiology and Community Health More from this journal
Volume:
75
Issue:
6
Pages:
496-500
Publication date:
2021-01-05
Acceptance date:
2020-12-16
DOI:
EISSN:
1470-2738
ISSN:
0143-005X


Language:
English
Keywords:
Pubs id:
1151140
Local pid:
pubs:1151140
Deposit date:
2020-12-22
ARK identifier:

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