Journal article
Human hookworm infection enhances mycobacterial growth inhibition and associates with reduced risk of tuberculosis infection
- Abstract:
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Soil-transmitted helminths and Mycobacterium tuberculosis frequently coincide geographically and it is hypothesized that gastrointestinal helminth infection may exacerbate tuberculosis (TB) disease by suppression of Th1 and Th17 responses. However, few studies have focused on latent TB infection (LTBI), which predominates globally. We performed a large observational study of healthy adults migrating from Nepal to the UK (n = 645). Individuals were screened for LTBI and gastrointestinal parasi...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.6MB)
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- Publisher copy:
- 10.3389/fimmu.2018.02893
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Authors
Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Immunology Journal website
- Volume:
- 9
- Publication date:
- 2018-12-14
- Acceptance date:
- 2018-11-26
- DOI:
- EISSN:
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1664-3224
Item Description
- Keywords:
- Pubs id:
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pubs:955378
- UUID:
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uuid:ea2a99ef-7960-451f-8271-ba4bd3a60139
- Local pid:
- pubs:955378
- Deposit date:
- 2019-01-03
Terms of use
- Copyright holder:
- O'Shea et al
- Copyright date:
- 2018
- Notes:
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© 2018 O'Shea, Fletcher, Muller, Tanner, Matsumiya, Bailey, Jones, Smith, Koh, Horsnell, Beeching, Dunbar, Wilson, Cunningham and McShane.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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