Journal article icon

Journal article

Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma brucei.

Abstract:

Adenylate kinases occur classically as cytoplasmic and mitochondrial enzymes, but the expression of seven adenylate kinases in the flagellated protozoan parasite Trypanosoma brucei (order, Kinetoplastida; family, Trypanosomatidae) easily exceeds the number of isoforms previously observed within a single cell and raises questions as to their location and function. We show that a requirement to target adenylate kinase into glycosomes, which are unique kinetoplastid-specific microbodies of the p...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1074/jbc.m413821200

Authors


Expand authors...
Journal:
The Journal of biological chemistry
Volume:
280
Issue:
12
Pages:
11781-11789
Publication date:
2005-03-05
DOI:
EISSN:
1083-351X
ISSN:
0021-9258
URN:
uuid:ea0b774b-5734-44dc-ac16-79736cf073ed
Source identifiers:
29327
Local pid:
pubs:29327

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP