Journal article
Diastereocontrolled synthesis of hydroxylated lactams
- Abstract:
- Highly diastereoselective reductions and organometallic additions in bicyclic lactams have been observed, which appear to result either from a stereoelectronic interaction of the pyramidalised nitrogen lone pair or from steric interactions in the bicyclic system. These products can be readily deprotected to give hydroxylated lactams.
- Publication status:
- Published
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- Publisher copy:
- 10.1039/b108056n
Authors
- Journal:
- JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 More from this journal
- Volume:
- 2
- Issue:
- 1
- Pages:
- 80-90
- Publication date:
- 2002-01-01
- DOI:
- EISSN:
-
1364-5463
- ISSN:
-
1472-7781
- Language:
-
English
- Pubs id:
-
pubs:38024
- UUID:
-
uuid:ea036957-ab5f-42e6-b3c4-315d6b5e566a
- Local pid:
-
pubs:38024
- Source identifiers:
-
38024
- Deposit date:
-
2012-12-19
- ARK identifier:
Terms of use
- Copyright date:
- 2002
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