Journal article
The global and regional prevalence of abdominal aortic aneurysms: a systematic review and modelling analysis
- Abstract:
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Objective: To estimate the global and regional prevalence and cases of abdominal aortic aneurysms (AAAs) in 2019 and to evaluate major associated factors.
Background: Understanding the global prevalence of AAA is essential for optimizing health services and reducing mortality from reputed AAA.
Methods: PubMed, MEDLINE, and Embase were searched for articles published until October 11, 2021. Population-based studies that reported AAA prevalence in the general population, defined AAA as an aortic diameter of 30 mm or greater with ultrasonography or computed tomography. A multilevel mixed-effects meta-regression approach was used to establish the relation between age and AAA prevalence for high-demographic sociodemographic index and low-and middle-sociodemographic index countries. Odds ratios of AAA associated factors were pooled using a random-effects method.
Results: We retained 54 articles across 19 countries. The global prevalence of AAA among persons aged 30 to 79 years was 0.92% (95% CI, 0.65–1.30), translating to a total of 35.12 million (95% CI, 24.94–49.80) AAA cases in 2019. Smoking, male sex, family history of AAA, advanced age, hypertension, hypercholesterolemia, obesity, cardiovascular disease, cerebrovascular disease, claudication, peripheral artery disease, pulmonary disease, and renal disease were associated with AAA. In 2019, the Western Pacific region had the highest AAA prevalence at 1.31% (95% CI, 0.94–1.85), whereas the African region had the lowest prevalence at 0.33% (95% CI, 0.23–0.48).
Conclusions: A substantial proportion of people are affected by AAA. There is a need to optimize epidemiological studies to promptly respond to at-risk and identified cases to improve outcomes.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 553.2KB, Terms of use)
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- Publisher copy:
- 10.1097/sla.0000000000005716
- Publisher:
- Lippincott, Williams & Wilkins
- Journal:
- Annals of Surgery More from this journal
- Volume:
- 277
- Issue:
- 6
- Pages:
- 912-919
- Publication date:
- 2022-09-30
- Acceptance date:
- 2012-09-01
- DOI:
- EISSN:
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1528-1140
- ISSN:
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0003-4932
- Pmid:
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36177847
- Language:
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English
- Keywords:
- Pubs id:
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1281672
- Local pid:
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pubs:1281672
- Deposit date:
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2022-11-30
Terms of use
- Copyright holder:
- Song et al.
- Copyright date:
- 2022
- Rights statement:
- Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
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