- Abstract:
-
Learning and memory processes critically involve the orchestrated regulation of de novo protein synthesis. On the other hand it has become clear that regulated protein degradation also plays a major role in neuronal plasticity and learning behavior. One of the key pathways mediating protein degradation is proteosomal protein destruction. The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that targets proteins for proteosomal degradation by the 26S proteasome. While the...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1101/lm.1998411
-
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- Journal:
- Learning and memory (Cold Spring Harbor, N.Y.)
- Volume:
- 18
- Issue:
- 1
- Pages:
- 49-57
- Publication date:
- 2011-01-05
- DOI:
- EISSN:
-
1549-5485
- ISSN:
-
1072-0502
- URN:
-
uuid:e9f4d5f7-301a-4ef9-9699-5339001e2b85
- Source identifiers:
-
110192
- Local pid:
- pubs:110192
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
The anaphase promoting complex is required for memory function in mice.
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