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Journal article

The anaphase promoting complex is required for memory function in mice.

Abstract:

Learning and memory processes critically involve the orchestrated regulation of de novo protein synthesis. On the other hand it has become clear that regulated protein degradation also plays a major role in neuronal plasticity and learning behavior. One of the key pathways mediating protein degradation is proteosomal protein destruction. The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that targets proteins for proteosomal degradation by the 26S proteasome. While the...

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Publication status:
Published

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Publisher copy:
10.1101/lm.1998411

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Journal:
Learning and memory (Cold Spring Harbor, N.Y.)
Volume:
18
Issue:
1
Pages:
49-57
Publication date:
2011-01-05
DOI:
EISSN:
1549-5485
ISSN:
1072-0502
URN:
uuid:e9f4d5f7-301a-4ef9-9699-5339001e2b85
Source identifiers:
110192
Local pid:
pubs:110192

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