Menstrual irregularity in women with acromegaly.

Journal article

Menstrual irregularity is common in women with acromegaly, occurring in 40-84%. Although it has been attributed to gonadotropin deficiency and/or PRL excess, it has not been evaluated in detail, and its pathogenesis is not well understood. To explore the various possible pathogenic mechanisms, we have analyzed the clinical, endocrinological, and radiological characteristics of 47 women with active acromegaly within the reproductive age range (15-41 yr) with respect to their menstrual pattern;...

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Authors: Kaltsas, G; Mukherjee, J; Jenkins, P; Satta, M; Islam, N

• Publication status: Published
• Journal: Journal of clinical endocrinology and metabolism
• Volume: 84
• Issue: 8
• Pages: 2731-2735
• Publication date: 1999-08-01
• DOI: 10.1210/jc.84.8.2731
• EISSN: 1945-7197
• ISSN: 0021-972X
• Language: English
• Keywords: Estradiol; Pituitary Gland; Menstruation Disturbances; Sex Hormone-Binding Globulin; Human Growth Hormone; Luteinizing Hormone; Acromegaly; Follicle Stimulating Hormone; Humans; Adolescent; Adult; Female