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The impact of cell crowding and active cell movement on vascular tumour growth

Abstract:

A multiscale model for vascular tumour growth is presented which includes systems of ordinary differential equations for the cell cycle and regulation of apoptosis in individual cells, coupled to partial differential equations for the spatio- temporal dynamics of nutrient and key signalling chemicals. Furthermore, these subcellular and tissue layers are incorporated into a cellular automaton framework for cancerous and normal tissue with an embedded vascular network. The model is the extensio...

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Publication status:
Published

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Publisher copy:
10.3934/nhm.2006.1.515

Authors


Betteridge, R More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Alarcon, T More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Volume:
1
Issue:
4
Pages:
515-535
Publication date:
2006-12-05
DOI:
ISSN:
1556-1801
URN:
uuid:e9e53702-bbf6-44b4-ad87-3e9970513e84
Source identifiers:
31361
Local pid:
pubs:31361

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