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Cerebral subcortical small vessel disease in subjects with pathologically confirmed Alzheimer disease: a clinicopathologic study in the Oxford Project to Investigate Memory and Ageing (OPTIMA).

Abstract:

The understanding of how cerebrovascular disease (CVD) contributes to dementia is hampered by a lack of agreed and validated pathologic methods to accord weight to the contribution of different aspects of CVD to dementia. A previous study from the Oxford Project to Investigate Memory and Ageing (OPTIMA) validated a scheme for assessing the contribution of subcortical small vessel disease (SVD) toward dementia in the elderly by showing a significant inverse relationship between the severity of...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Joachim, C More by this author
Christie, S More by this author
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Institution:
University of Oxford
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Journal:
Alzheimer disease and associated disorders
Volume:
28
Issue:
1
Pages:
30-35
Publication date:
2014-01-05
DOI:
EISSN:
1546-4156
ISSN:
0893-0341
URN:
uuid:e9e40b1f-5f3f-4fb0-ace4-a6e0a4319704
Source identifiers:
411101
Local pid:
pubs:411101

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