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Journal article

Vaccination against nicotine: an emerging therapy for tobacco dependence.

Abstract:

Tobacco dependence is an addiction characterised by compulsive drug-seeking and drug-taking behavior and intensive craving in the absence of tobacco. Nicotine is the major addictive component of tobacco and acts on the reward system in the brain. Together with strong conditional reinforcements, unaided smoking cessation attempts are notoriously unsuccessful and even the most recently introduced pharmacotherapy, varenicline, only achieves a 23% continuous abstinence rate after 1 year. Vaccinat...

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Publication status:
Published

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Publisher copy:
10.1517/13543784.16.11.1775

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Role:
Author
Journal:
Expert opinion on investigational drugs
Volume:
16
Issue:
11
Pages:
1775-1783
Publication date:
2007-11-05
DOI:
EISSN:
1744-7658
ISSN:
1354-3784
URN:
uuid:e9cadaa3-ffcd-4ade-b6cd-1198930ab035
Source identifiers:
469722
Local pid:
pubs:469722

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