Journal article

The use of butane diacetals of glycolic acid as precursors for the synthesis of the phytotoxic calmodulin inhibitor herbarumin II

Abstract:: The total synthesis of phytotoxic nonenolide herbarumin II (1) has been achieved by implementation of butane diacetal (BDA)-desymmetrised glycolate building blocks. Three of the four stereogenic centres present in the key coupling fragments were generated from both enantiomeric forms of the BDA building block in highly diastereoselective alkylation and aldol reactions.

Publication status:: Published

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APA Style

Diez, E., Dixon, D., Ley, S., Polara, A., & Rodriguez, F. (2003). The use of butane diacetals of glycolic acid as precursors for the synthesis of the phytotoxic calmodulin inhibitor herbarumin II. HELVETICA CHIMICA ACTA, 86(11), 3717–3729.

MLA Style

Diez, E, et al. “The Use of Butane Diacetals of Glycolic Acid as Precursors for the Synthesis of the Phytotoxic Calmodulin Inhibitor Herbarumin II.” HELVETICA CHIMICA ACTA, vol. 86, no. 11, 2003, pp. 3717–29.

Chicago Style

Diez, E, D Dixon, S Ley, A Polara, and F Rodriguez. 2003. “The Use of Butane Diacetals of Glycolic Acid as Precursors for the Synthesis of the Phytotoxic Calmodulin Inhibitor Herbarumin II.” HELVETICA CHIMICA ACTA 86 (11): 3717–29.
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Publisher copy:: 10.1002/hlca.200390314

Authors

+ Diez, E More by this author

Role:: Author

+ Dixon, D More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Ley, S More by this author

Role:: Author

+ Polara, A More by this author

Role:: Author

+ Rodriguez, F More by this author

Role:: Author

Journal:: HELVETICA CHIMICA ACTA More from this journal
Volume:: 86
Issue:: 11
Pages:: 3717-3729
Publication date:: 2003-01-01
DOI:: 10.1002/hlca.200390314
EISSN:: 1522-2675
ISSN:: 0018-019X

Language:: English
Pubs id:: pubs:52080
UUID:: uuid:e9c3c245-e4e1-4f07-abdf-92a79175f7cd
Local pid:: pubs:52080
Source identifiers:: 52080
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_e9c3c245e4e14f07abdf92a79175f7cd

Terms of use

Copyright date:: 2003

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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