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Journal article

Distinct but critical roles for integrin alphaIIbbeta3 in platelet lamellipodia formation on fibrinogen, collagen-related peptide and thrombin.

Abstract:

Integrins are the major receptor type known to facilitate cell adhesion and lamellipodia formation on extracellular matrix proteins. However, collagen-related peptide and thrombin have recently been shown to mediate platelet lamellipodia formation when presented as immobilized surfaces. The aims of this study were to establish if there exists a role for the platelet integrin alpha(IIb)beta(3) in this response; and if so, whether signalling from the integrin is required for lamellipodia format...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Journal:
The FEBS journal
Volume:
273
Issue:
22
Pages:
5032-5043
Publication date:
2006-11-05
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
URN:
uuid:e9c18f50-450a-4179-a646-ade79125b743
Source identifiers:
100045
Local pid:
pubs:100045

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