Cysteine and obesity: consistency of the evidence across epidemiologic, animal and cellular studies.

Journal article

PURPOSE OF REVIEW: The concentrations of several plasma amino acids increase in obesity. Notably, plasma total concentrations of the sulphur amino acid cysteine (tCys) are linearly associated with fat mass in large population studies. Animal and cellular experiments support the concept that cysteine may be obesogenic. Here we review experimental and epidemiologic findings linking cysteine and related compounds with fat regulation and obesity. RECENT FINDINGS: tCys, and to a lesser extent cys...

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Authors: Elshorbagy, A; Kozich, V; Smith, A; Refsum, H

• Publication status: Published
• Journal: Current opinion in clinical nutrition and metabolic care
• Volume: 15
• Issue: 1
• Pages: 49-57
• Publication date: 2012-01-01
• DOI: 10.1097/mco.0b013e32834d199f
• EISSN: 1473-6519
• ISSN: 1363-1950
• Language: English
• Keywords: Adipose Tissue; Enzymes; Glutathione; Lipid Metabolism; Energy Metabolism; Animals; Obesity; Body Weight; Cystathionine; Humans; Adipogenesis; Cysteine