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Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study

Abstract:
Background Artemisinin resistance in Plasmodium falciparum threatens to reduce the efficacy of artemisinin combination therapies (ACTs), thus compromising global efforts to eliminate malaria. Recent treatment failures with dihydroartemisinin-piperaquine, the current first-line ACT in Cambodia, suggest that piperaquine resistance may be emerging in this country. We explored the relation between artemisinin resistance and dihydroartemisinin–piperaquine failures, and sought to ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/S1473-3099(15)00487-9

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National Institute of Allergy and Infectious Diseases More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet Infectious Diseases Journal website
Volume:
16
Issue:
3
Pages:
357-365
Publication date:
2016-01-01
DOI:
ISSN:
1473-3099
URN:
uuid:e9b918d1-3cba-4b3f-a159-5dfd439f274e
Source identifiers:
609848
Local pid:
pubs:609848

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