Journal article
Hyporesponsiveness of intestinal dendritic cells to TLR stimulation is limited to TLR4.
- Abstract:
-
Dendritic cells (DCs) are crucial to intestinal immune regulation because of their roles in inducing protective immunity against pathogens while maintaining tolerance to commensal bacteria. Nonetheless, relatively little is known about intestinal DC responsiveness to innate immune stimuli via TLRs. We have previously shown that DCs migrating from the rat intestine in lymph (iLDCs) are hyporesponsive to LPS stimulation, thus possibly preventing harmful immune responses being induced to commens...
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- Publication status:
- Published
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- Publisher copy:
- 10.4049/jimmunol.0802318
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Authors
Bibliographic Details
- Journal:
- Journal of Immunology
- Volume:
- 182
- Issue:
- 4
- Pages:
- 2405-2415
- Publication date:
- 2009-02-01
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
11405
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:11405
- UUID:
-
uuid:e9a0bf0a-c762-4155-8ff6-e11b797595a1
- Local pid:
- pubs:11405
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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