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LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan.

Abstract:

The extracellular matrix glycosaminoglycan hyaluronan (HA) is an abundant component of skin and mesenchymal tissues where it facilitates cell migration during wound healing, inflammation, and embryonic morphogenesis. Both during normal tissue homeostasis and particularly after tissue injury, HA is mobilized from these sites through lymphatic vessels to the lymph nodes where it is degraded before entering the circulation for rapid uptake by the liver. Currently, however, the identities of HA b...

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Publication status:
Published

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Publisher copy:
10.1083/jcb.144.4.789

Authors


Banerji, S More by this author
Clasper, S More by this author
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Journal:
The Journal of cell biology
Volume:
144
Issue:
4
Pages:
789-801
Publication date:
1999-02-05
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
URN:
uuid:e97f7d82-c8e7-4f28-8616-f6f3512ce9ae
Source identifiers:
102544
Local pid:
pubs:102544

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