- Abstract:
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OBJECTIVE: The serotonin transporter (5-HTT) is a key target for selective serotonin reuptake inhibitors and may be involved in the pathophysiology of major depression. It is now possible to image 5-HTT directly in the human brain, but results from studies of acutely depressed patients have been inconsistent. The purpose of this study was to determine whether abnormalities in 5-HTT might be present in recovered depressed patients. METHOD: The authors measured the binding potential of 5-HTT us...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1176/appi.ajp.2007.06111933
-
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- Journal:
- The American journal of psychiatry
- Volume:
- 164
- Issue:
- 12
- Pages:
- 1858-1865
- Publication date:
- 2007-12-05
- DOI:
- EISSN:
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1535-7228
- ISSN:
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0002-953X
- URN:
-
uuid:e9646d63-45bd-4ee9-8ffc-545d8a617157
- Source identifiers:
-
139677
- Local pid:
- pubs:139677
- Copyright date:
- 2007
Journal article
5-HTT binding in recovered depressed patients and healthy volunteers: a positron emission tomography study with [11C]DASB.
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