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Journal article

Characteristics of the aortic elastic network and related phenotypes in seven inbred rat strains.

Abstract:

Extracellular matrix (ECM) molecules such as elastin and collagen provide mechanical support to the vessel wall and are essential for vascular function. Evidence that genetic factors influence aortic ECM composition and organization was concluded from our previous studies showing that the inbred Brown Norway (BN) rat differs significantly from the outbred Long-Evans (LE) and the inbred LOU rat with respect to both thoracic aortic elastin content and internal elastic lamina (IEL) rupture in th...

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Publication status:
Published

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Publisher copy:
10.1152/ajpheart.00544.2004

Authors


Behmoaras, J More by this author
Osborne-Pellegrin, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
American journal of physiology. Heart and circulatory physiology
Volume:
288
Issue:
2
Pages:
H769-H777
Publication date:
2005-02-05
DOI:
EISSN:
1522-1539
ISSN:
0363-6135
URN:
uuid:e9644dee-b721-433e-80da-c80dbfdd8c06
Source identifiers:
3675
Local pid:
pubs:3675

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