Journal article
S-adenosylmethionine in rat liver cirrhosis
- Abstract:
- An experimental model of cirrhosis in rats, by means carbon tetrachloride (CCl4) and ethanol during two months, was used to assess the effectiveness of S-adenosylmethionine. Histological studies of the liver and examination of different biochemical parameters of hepatic function were also employed. Bilirubin and lactic acid levels decreased significantly in the group treated with S-adenosylmethionine in comparison with the CCl4 + ethanol group. Histologic liver studies showed a significant improvement relative to fatty liver, Mallory bodies, infiltrate polymorphonuclear and perivenular fibrosis. A slight decrease in cirrhosis was observed in the animals treated with S- adenosylmethionine.
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Authors
- Journal:
- Research Communications in Substances of Abuse More from this journal
- Volume:
- 14
- Issue:
- 2-3
- Pages:
- 159-167
- Publication date:
- 1993-01-01
- ISSN:
-
0193-0818
- Language:
-
English
- Pubs id:
-
pubs:410715
- UUID:
-
uuid:e9635d72-c3e6-40e2-aeef-c68ad43dae12
- Local pid:
-
pubs:410715
- Source identifiers:
-
410715
- Deposit date:
-
2013-11-16
- ARK identifier:
Terms of use
- Copyright date:
- 1993
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