- Abstract:
-
Liquid chromatography combined with electrospray ionization mass spectrometry (LC/ESI-MS) has been used successfully for the characterization of biomolecules in proteomics in the last few years. This methodology relied largely on the use of reversed-phase chromatography, in particular C18-based resins, which are suitable for separation of peptides. Here we show that polymeric [polystyrene divinylbenzene] monolithic columns can be used to separate peptide mixtures faster and at a higher resolu...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/rcm.2563
-
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- Journal:
- Rapid communications in mass spectrometry : RCM
- Volume:
- 20
- Issue:
- 14
- Pages:
- 2074-2080
- Publication date:
- 2006
- DOI:
- EISSN:
-
1097-0231
- ISSN:
-
0951-4198
- URN:
-
uuid:e95996b8-e88c-4362-888d-4bfd1c9f5367
- Source identifiers:
-
6763
- Local pid:
- pubs:6763
- Copyright date:
- 2006
Journal article
Ultra-fast tandem mass spectrometry scanning combined with monolithic column liquid chromatography increases throughput in proteomic analysis.
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