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Rat melanin concentrating hormone does not modify the release of CRH-41 from rat hypothalamus or ACTH from the anterior pituitary in vitro.

Abstract:

It has been suggested that melanin concentrating hormone (MCH) possesses potent corticotrophin (ACTH) inhibitory activity, on the basis of the inhibitory effects displayed by salmon MCH on ACTH release from either trout or rat isolated pituitary fragments. Recently, rat MCH has been characterised, and this prompted us to investigate the putative inhibitory activity of synthetic rat MCH on basal and stimulated ACTH secretion from freshly-dispersed rat pituitary cells or incubated rat pituitary...

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Publication status:
Published

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Publisher copy:
10.1677/joe.0.127r001

Authors


Navarra, P More by this author
Tsagarakis, S More by this author
Besser, GM More by this author
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Journal:
The Journal of endocrinology
Volume:
127
Issue:
1
Pages:
R1-R4
Publication date:
1990-10-05
DOI:
EISSN:
1479-6805
ISSN:
0022-0795
URN:
uuid:e9583344-40c7-4d24-9d26-4c5ae50b9e56
Source identifiers:
138154
Local pid:
pubs:138154

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