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Journal article

Comparison of the solution structures of intramolecular DNA triple helices containing adjacent and non-adjacent CG.C+ triplets.

Abstract:

The solution conformations of the intramolecular triple helices d(AGAAGA-X-TCTTCT-X-TC+TTC+T) and d(AAGGAA-X-TTCCTT-X-TTC+C+TT) (X = non-nucleotide linker) have been determined by NMR.1H NMR spectra in H2O showed that the third strand cytosine residues are fully paired with the guanine residues, each using two Hoogsteen hydrogen bonds. Determination of the13C chemical shifts of the cytosine C6 and C5 and their one-bond coupling constants (1 J CH) conclusively showed that the Hoogsteen cytosin...

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Publication status:
Published

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Publisher copy:
10.1093/nar/26.16.3677

Authors


Asensio, JL More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
Nucleic acids research
Volume:
26
Issue:
16
Pages:
3677-3686
Publication date:
1998-08-05
DOI:
EISSN:
1362-4962
ISSN:
0305-1048
URN:
uuid:e9550e61-27a5-4f62-b18a-f4ae4aa1a132
Source identifiers:
400265
Local pid:
pubs:400265

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