Journal article

STUDIES ON THE EXCHANGE OF VALINE-OXYGEN DURING THE BIOSYNTHESIS OF DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE

Abstract:: Incorporation of [4-2H6,18O2]-valine into δ-(L)-α-aminoadipoyl)-L-cysteinyl-D-valine (ACV), by intact cells of Cephalosporium acremonium, demonstrated the intracellular exchange of one and both valine oxygen atoms. Incubation of [18O2]-valine with the purified ACV synthetase from C. acremonium gave exclusive incorporation of a single 18O label into ACV, consistent witheffectively non-reversible formation of a covalent valinoyl-ACV synthetase intermediate under in vitro conditions. © 1992.

Publication status:: Published

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APA Style

Baldwin, J., Adlington, R., Bird, J., Field, R., Ocallaghan, N., & Schofield, C. (1992). STUDIES ON THE EXCHANGE OF VALINE-OXYGEN DURING THE BIOSYNTHESIS OF DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE. TETRAHEDRON, 48(6), 1099–1108.

MLA Style

Baldwin, J, et al. “STUDIES ON THE EXCHANGE OF VALINE-OXYGEN DURING THE BIOSYNTHESIS OF DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE.” TETRAHEDRON, vol. 48, no. 6, 1992, pp. 1099–108.

Chicago Style

Baldwin, J, R Adlington, J Bird, R Field, N Ocallaghan, and C Schofield. 1992. “STUDIES ON THE EXCHANGE OF VALINE-OXYGEN DURING THE BIOSYNTHESIS OF DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE.” TETRAHEDRON 48 (6): 1099–1108.
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Publisher copy:: 10.1016/S0040-4020(01)88205-3

Authors

+ Baldwin, J More by this author

Role:: Author

+ Adlington, R More by this author

Role:: Author

+ Bird, J More by this author

Role:: Author

+ Field, R More by this author

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+ Ocallaghan, N More by this author

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Journal:: TETRAHEDRON More from this journal
Volume:: 48
Issue:: 6
Pages:: 1099-1108
Publication date:: 1992-02-07
DOI:: 10.1016/S0040-4020(01)88205-3
ISSN:: 0040-4020

Language:: English
Keywords:: PENICILLIN

BIOSYNTHESIS

CEPHALOSPORIUM ACREMONIUM

DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE (ACV)

[18O2]-VALINE INCORPORATION
Pubs id:: pubs:43845
UUID:: uuid:e94d4da9-1e79-46ff-82ba-19db925e94e6
Local pid:: pubs:43845
Source identifiers:: 43845
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_e94d4da91e7946ff82ba19db925e94e6

Terms of use

Copyright date:: 1992

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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