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UltraRapid communications : vascular superoxide production by NAD(P)H OxidaseAssociation with endothelial dysfunction and clinical risk factors

Abstract:

Superoxide anion plays important roles in vascular disease states. Increased superoxide production contributes to reduced nitric oxide (NO) bioactivity and endothelial dysfunction in experimental models of vascular disease. We measured superoxide production by NAD(P)H oxidase in human blood vessels and examined the relationships between NAD(P)H oxidase activity, NO-mediated endothelial function, and clinical risk factors for atherosclerosis. Endothelium-dependent vasorelaxations and direct me...

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Publisher copy:
10.1161/01.res.86.9.1008

Authors


Journal:
Circulation research More from this journal
Volume:
86
Issue:
9
Pages:
1008
Publication date:
2000-05-01
DOI:
EISSN:
1524-4571
ISSN:
0009-7330


Language:
English
Pubs id:
pubs:105052
UUID:
uuid:e94adc6d-6cc8-40fd-98bb-31adc958879d
Local pid:
pubs:105052
Source identifiers:
105052
Deposit date:
2012-12-19
ARK identifier:

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