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CRISPR dynamics during the interaction between bacteria and phage in the first year of life

Abstract:

Gut microbiomes in infancy have a profound impact on health in adulthood. CRISPRs play an essential role in the interaction between bacteria and phages. However, the dynamics of CRISPRs in gut microbiomes during early life are poorly understood. In this study, using shotgun metagenomic sequencing data from 82 Swedish infants’ gut microbiomes, 1882 candidate CRISPRs were identified, and their dynamics were analysed. We found large-scale turnover of CRISPRs and their spacers during the first ye...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1099/mgen.0.001053

Authors


Publisher:
Microbiology Society
Journal:
Microbial Genomics More from this journal
Volume:
9
Issue:
7
Article number:
1053
Publication date:
2023-07-04
Acceptance date:
2023-05-26
DOI:
EISSN:
2057-5858
ISSN:
2057-5858
Pmid:
37402176
Language:
English
Keywords:
Pubs id:
1489819
Local pid:
pubs:1489819
Deposit date:
2024-03-15

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