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How threshold behaviour affects the use of subgraphs for network comparison.

Abstract:

MOTIVATION: A wealth of protein-protein interaction (PPI) data has recently become available. These data are organized as PPI networks and an efficient and biologically meaningful method to compare such PPI networks is needed. As a first step, we would like to compare observed networks to established network models, under the aspect of small subgraph counts, as these are conjectured to relate to functional modules in the PPI network. We employ the software tool GraphCrunch with the Graphlet ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
Journal:
Bioinformatics (Oxford, England) More from this journal
Volume:
26
Issue:
18
Pages:
i611-i617
Publication date:
2010-09-01
DOI:
EISSN:
1367-4811
ISSN:
1367-4803
Language:
English
Keywords:
Pubs id:
pubs:97507
UUID:
uuid:e94179aa-0a5f-4255-9dc8-51bc2091802c
Local pid:
pubs:97507
Source identifiers:
97507
Deposit date:
2012-12-19

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