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Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysis.

Abstract:

An understanding of the neurobiological correlates of vulnerability to psychosis is fundamental to research on schizophrenia. We systematically reviewed data from studies published from 1992 to 2006 on the neurocognitive correlates (as measured by fMRI) of increased vulnerability to psychosis. We also conducted a meta-analysis of abnormalities of activation in the prefrontal cortex (PFC) in high-risk and first episode subjects, and reviewed neuroimaging studies of high-risk subjects that used...

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
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Journal:
Neuroscience and biobehavioral reviews
Volume:
31
Issue:
4
Pages:
465-484
Publication date:
2007-01-01
DOI:
EISSN:
1873-7528
ISSN:
0149-7634
URN:
uuid:e9386269-8b1e-4fc4-8a66-571bbf98c53b
Source identifiers:
403460
Local pid:
pubs:403460

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