Journal article icon

Journal article

NAADP influences excitation-contraction coupling by releasing calcium from lysosomes in atrial myocytes

Abstract:

In atrial myocytes, the sarcoplasmic reticulum (SR) has an essential role in regulating the force of contraction as a consequence of its involvement in excitation-contraction coupling (ECC). Nicotinic acid adenine dinucleotide phosphate (NAADP) is a Ca 2+ mobilizing messenger that acts to release Ca 2+ from an acidic store in mammalian cells. The photorelease of NAADP in atrial myocytes increased Ca 2+ transient amplit...

Expand abstract

Actions


Access Document


Publisher copy:
10.1016/j.ceca.2011.07.007

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Journal:
Cell Calcium More from this journal
Volume:
50
Issue:
5
Pages:
449-458
Publication date:
2011-11-01
DOI:
EISSN:
1532-1991
ISSN:
0143-4160
Language:
English
Keywords:
Pubs id:
pubs:192983
UUID:
uuid:e9222fa2-5a17-4cfc-a898-bc80c76a9907
Local pid:
pubs:192983
Source identifiers:
192983
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP