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Journal article

Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages.

Abstract:

Candida albicans is a dimorphic yeast that enters macrophages (Mphi) via the beta-glucan receptor dectin-1. Phagocytosis of C. albicans is characterized by actin polymerization, Syk kinase activation and rapid acquisition of phagolysosomal markers. In mice, C. albicans are able to resist the harsh environment of the phagosome and form pseudohyphae inside the phagolysosomal compartment, eventually extending from the Mphi. In this study, we investigated these unique C. albicans phagosomes and f...

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Publication status:
Published

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Publisher copy:
10.1159/000173694

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Journal:
Journal of innate immunity
Volume:
1
Issue:
3
Pages:
244-253
Publication date:
2009-01-01
DOI:
EISSN:
1662-8128
ISSN:
1662-811X
Source identifiers:
25182
Language:
English
Keywords:
Pubs id:
pubs:25182
UUID:
uuid:e91f681d-f0a3-4070-a5e8-793f5fc91e1b
Local pid:
pubs:25182
Deposit date:
2012-12-19

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