Long term effects of a first pregnancy on serum concentrations of dehydroepiandrosterone sulfate and dehydroepiandrosterone.

Journal article

A previous paper in this journal reported that first pregnancy was followed by a marked decrease in dehydro-epiandrosterone sulfate (DHAS) and dehydroepiandrosterone (DHA) levels. We report here confirmatory observations from cross-sectional measurements in 460 women. In premenopausal subjects (n = 306), the mean DHAS level was 21% lower (P = 0.005) and the mean DHA level was 32% lower (P less than 0.001) in parous than in nulliparous women. Neither DHAS nor DHA was related to parity in postmenopausal women (n = 154).

Authors: Key, T; Pike, M; Wang, D; Moore, J

• Journal: Journal of clinical endocrinology and metabolism
• Volume: 70
• Issue: 6
• Pages: 1651-1653
• Publication date: 1990-06-01
• DOI: 10.1210/jcem-70-6-1651
• EISSN: 1945-7197
• ISSN: 0021-972X
• Language: English
• Keywords: Age Factors; Body Mass Index; Dehydroepiandrosterone; Aged; Dehydroepiandrosterone Sulfate; Parity; Middle Aged; Adult; Menopause; Humans; Female