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Journal article

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Abstract:

Background: Casirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike glycoprotein, blocking viral entry into host cells. We aimed to evaluate the efficacy and safety of casirivimab and imdevimab administered in combination in patients admitted to hospital with COVID-19.

Methods: RECOVERY is a randomised, controlled, open-label platform trial comparing s...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S0140-6736(22)00163-5

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author

Contributors


Publisher:
Elsevier
Journal:
Lancet More from this journal
Volume:
399
Issue:
10325
Pages:
665-676
Publication date:
2022-02-12
Acceptance date:
2021-12-14
DOI:
EISSN:
1474-547X
ISSN:
0140-6736


Language:
English
Keywords:
Pubs id:
1225614
Local pid:
pubs:1225614
Deposit date:
2021-12-16

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