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Journal article

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.

Abstract:

The numbers and distribution of the neurofibrillary tangles and neuritic plaques have been determined in several areas of the neocortex in brains affected by various degrees of severity of Alzheimer disease. The homotypical cortex of the "association" areas of the temporal, parietal, and frontal lobes are severely involved, whereas the motor, somatic sensory, and primary visual areas are virtually unaffected. The neurofibrillary tangles are mainly in the supra- and infragranular layers, parti...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.82.13.4531

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Proceedings of the National Academy of Sciences of the United States of America More from this journal
Volume:
82
Issue:
13
Pages:
4531-4534
Publication date:
1985-07-01
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Language:
English
Keywords:
Pubs id:
pubs:35369
UUID:
uuid:e9062ec9-c0e1-4f90-a676-9596f6d8f02d
Local pid:
pubs:35369
Source identifiers:
35369
Deposit date:
2012-12-19

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