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HIV-1 viral load and resistance in genital secretions in patients taking protease-inhibitor-based second-line therapy in Africa

Abstract:

Background: HIV is transmitted primarily through sexual intercourse, and the objective of this study was therefore to assess whether there is occult viral replication and resistance in genital secretions in patients on protease inhibitor (PI)-based second-line therapy. Methods: HIV-infected adults taking ritonavir-boosted lopinavir with either two NRTIs, raltegravir, or as monotherapy for 96 weeks were enrolled at seven clinical sites in Uganda. Viral load (VL) was measured in cervico-vagina...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3851/IMP3200

Authors


Publisher:
International Medical Press
Journal:
Antiviral Therapy More from this journal
Publication date:
2017-10-12
Acceptance date:
2017-10-01
DOI:
ISSN:
1359-6535
Pubs id:
pubs:734450
UUID:
uuid:e903aaa5-460e-4ed9-9f2e-ed73e2acba50
Local pid:
pubs:734450
Source identifiers:
734450
Deposit date:
2017-10-06

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