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Immunological effects of IgT synthesized by theta-positive cell lines.

Abstract:

The effects of immunoglobulin (Ig) purified by affinity chromatography from two cultured T cell lines on in vitro immune responses was studied. IgT purified from both EL-4 and WEHI-22 suppressed the thymus-dependent IgM response, but had no effect on the thymus-independent IgM response. In contrast, the IgG responses to both thymus-dependent and independent antigens were augmented at optimal concentrations of IgT. Ig of B cell origin--serum Ig, myeloma Ig, B cell surface Ig -- did not have an...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830050615

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Boylston, A More by this author
Journal:
European journal of immunology
Volume:
5
Issue:
6
Pages:
429-431
Publication date:
1976-06-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:e8d65769-7608-4ffb-a2f0-413909d191b3
Source identifiers:
481832
Local pid:
pubs:481832

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