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Aetiologies, neuroradiological features, and risk factors for mortality and long-term neurosequelae of febrile coma in Malawian children: a prospective cohort study

Abstract:

Background: Children in febrile coma in Africa are frequently hospitalised, with poorer outcomes than those in high-income settings. Cerebral malaria is historically the most common cause of febrile coma. Due to limited diagnostic and radiological resources and a decrease in malaria prevalence, there might be under-recognition of non-malarial coma. However, prospective data are scarce. We aimed to determine causes, neuroradiological features, risk factors for mortality, an...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/s2214-109x(25)00054-3

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author


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Funder identifier:
https://ror.org/00by1q217


Publisher:
Elsevier
Journal:
Lancet Global Health More from this journal
Volume:
13
Issue:
6
Pages:
e1057-e1071
Publication date:
2025-04-22
Acceptance date:
2025-01-30
DOI:
EISSN:
2214-109X


Language:
English
Pubs id:
2120266
Local pid:
pubs:2120266
Deposit date:
2025-05-19
ARK identifier:

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