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BIOSYNTHETIC PRECURSORS OF VALCLAVAM

Abstract:
The biosynthesis of valclavam was investigated by feeding radiolabelled potential precursors to fermentations of Streptomyces antibioticus ssp antibioticus Tü 1718. The preliminary results indicate that the primary metabolic precursors of valclavam are L-valine, L-arginine, L-methionine and a 3-C pool metabolite and suggest a common biosynthetic origin for clavulanic acid and valclavam. © 1994.
Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
TETRAHEDRON LETTERS More from this journal
Volume:
35
Issue:
17
Pages:
2779-2782
Publication date:
1994-04-25
DOI:
ISSN:
0040-4039
Pubs id:
pubs:44402
UUID:
uuid:e8a9e57b-c52b-4422-9964-d530807fffaa
Local pid:
pubs:44402
Source identifiers:
44402
Deposit date:
2012-12-19

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