Corticosteroids for the management of ulcerative colitis and Crohn's disease.

Journal article

Corticosteroids are of proven value for the treatment of active ulcerative colitis and Crohn's disease, but are of little value for the maintenance of remission. The development of new steroid compounds with low systemic bioavailability should allow higher doses to be given for longer periods without risking serious adverse reactions.

Authors: Jewell, D

• Publication status: Published
• Journal: Gastroenterology clinics of North America
• Volume: 18
• Issue: 1
• Pages: 21-34
• Publication date: 1989-03-01
• EISSN: 1558-1942
• ISSN: 0889-8553
• Language: English
• Keywords: Humans; Crohn Disease; Administration, Topical; Drug Administration Schedule; Adrenal Cortex Hormones; Enema; Colitis, Ulcerative